Simple diagnostic model can accurately predict risk for community acquired pneumonia in children

Children's Health

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Diagnosis of community acquired pneumonia in children usually involves x-rays, despite recommendations to limit their use by professional societies. In efforts to reduce radiation exposure from x-rays in children and reinforce guideline compliance, researchers from Ann & Robert H. Lurie Children’s Hospital of Chicago and colleagues developed a simple diagnostic model that accurately predicts whether patients are at high risk or low risk for community acquired pneumonia, eliminating the need for x-ray confirmation. Their findings were published in the journal Pediatrics.

Our predictive model for community acquired pneumonia is a critical step toward safely reducing radiation exposure in children. For patients who are determined to be at low risk for pneumonia, we can also avoid unnecessary antibiotic use.”

Sriram Ramgopal, MD, Lead Author, Emergency Medicine Physician, Lurie Children’s and Assistant Professor of Pediatrics, Northwestern University Feinberg School of Medicine

Dr. Ramgopal and colleagues statistically derived their model based on the clinical history, symptoms and x-ray results of 1,142 patients, aged 3 months to 18 years who were evaluated for suspicion of community acquired pneumonia. They found three key variables with the strongest predictive value for either high risk or low risk of pneumonia – increasing age, fever duration and decreased breath sounds upon exam with a stethoscope.

“Since our model does not rely on lab results, it may allow for broader implementation in the primary care setting,” said senior author Todd Florin, MD, MSCE, Director of Research in Emergency Medicine at Lurie Children’s and Associate Professor of Pediatrics at Northwestern University Feinberg School of Medicine. “If validated by other centers, this model could be implemented using an online calculator of risk or through clinical decision support tools that can be embedded in the electronic medical record.”

Journal reference:

Ramgopal, S., et al. (2021) A Prediction Model for Pediatric Radiographic Pneumonia. Pediatrics. doi.org/10.1542/peds.2021-051405.

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